Disrupting a survival signal
نویسندگان
چکیده
منابع مشابه
Integrins mediate a neuronal survival signal for oligodendrocytes
Target-dependent survival of newly differentiated cells is an important part of neural development. In the case of myelin-forming oligodendrocytes, it matches the number of oligodendrocytes to the available axons [1]. In addition to growth factors, an axonal signal regulates this survival: when axons are transected, oligodendrocytes die and, conversely, when the number of axons is increased by ...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2013
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc3584